Sublingual sufentanil after orthopaedic and abdominal surgery: long-term outcome and safety
Authors' conclusion
SSTS sufficiently treated acute postoperative pain without incidence of POD and demonstrated good tolerability and overall ease. Postoperative pain improved significantly over time but 22% still reported chronic pain related to surgery. Technical issues with the identification thumb tag limited the feasibility of SSTS.
Study context
- Population
- Adults undergoing elective orthopaedic knee or abdominal surgery planned for patient-controlled analgesia (PCA), university hospital, November 2017–November 2021
- Participants
- 80 adults
- Outcome
- Incidence of postoperative chronic pain (PCP) and POD
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Daily pain experience, pre-operatively
89.2%
Daily pain experience at 3 months
45.7%
Daily pain experience at 12 months
22.5%
Postoperative delirium (POD) after surgery
0
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Overall satisfaction with SSTS | SSTS median 8.0 (IQR 3) /10 points |
Safety
| Outcome | Values |
|---|---|
| Difficulties handling SSTS requiring acute replacement of authentication tag | SSTS 51% |
Original publication
Sublingual sufentanil after orthopaedic and abdominal surgery: long-term outcome and safety. Perioper Med (Lond). Published 28 February 2025. doi:10.
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