Supraglottic Jet Oxygenation and Ventilation to Minimize Hypoxia in Patients Receiving Flexible Bronchoscopy Under Deep Sedation: A 3-Arm Randomized Controlled Trial
Authors' conclusion
SJOV via WNJ effectively reduces the incidence of hypoxia during FB under deep sedation.
Study context
- Population
- Adults scheduled for flexible bronchoscopy under deep sedationall analysed by ITT
- Participants
- 132 adults
- Comparison
- Nasal catheter (NC) vs low-pressure low-flow (LPLF) vs supraglottic jet oxygenation and ventilation (SJOV)
- NCn = 44reference
- LPLFn = 44reference
- SJOVn = 44
- Primary endpoint
- Hypoxia (SpO2 <90% lasting more than 5 seconds)
- Follow-up
- During FB
Methodological detailssingle-center, 3-arm
- Single-center
- 3-arm
Primary result
As reported in the abstract
RRP value
SJOV vs NC
0.11(98% CI 0.02–0.51)
P < 0.001SJOV vs LPLF
0.15(95% CI 0.04–0.61)
P < 0.001Secondary outcomes
Subclinical respiratory depression — SJOV vs NC
P < 0.001
| Outcome | NC | LPLF | SJOV | P value |
|---|---|---|---|---|
| Subclinical respiratory depressionSJOV vs LPLF | P < 0.001 | |||
| Severe hypoxia | — not stated in the abstract | — not stated in the abstract | 0 events |
— not stated in the abstract
Remedial interventions for hypoxia
- More remedial interventions needed with NC
Safety
Xerostomia
- Higher risk of xerostomia with SJOV
Severe adverse events
- No severe adverse event observed throughout the study
Original publication
Supraglottic Jet Oxygenation and Ventilation to Minimize Hypoxia in Patients Receiving Flexible Bronchoscopy Under Deep Sedation: A 3-Arm Randomized Controlled Trial. Anesth Analg. Published 24 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →