Cardiac arrest & resuscitation
Survival After Extracorporeal Cardiopulmonary Resuscitation Based on In-Hospital Cardiac Arrest and Cannulation Location: An Analysis of the Extracorporeal Life Support Organization Registry
Authors' conclusion
ECPR patients who experienced cardiac arrest in the ICU and in acute care hospital beds had increased odds of mortality compared with other locations. Moving patients for ECPR cannulation was not associated with improved outcomes.
Study context
- Population
- Patients having extracorporeal cardiopulmonary resuscitation (ECPR) for IHCA between 2020 and 2023 with data in the Extracorporeal Life Support Organization (ELSO) registry
- Participants
- 2,515 patients
- Exposure
- ICU vs Acute care bed vs Cardiac catheterization laboratory
- Outcome
- In-hospital mortality
Methodological detailsregistry analysis, multivariable logistic regression
- Registry analysis
- Multivariable logistic regression
Main finding
As reported in the abstract
In-hospital mortality by cardiac arrest location
Each group vs cardiac catheterization laboratoryAdjusted odds ratio (95% CI)P value
ICU
1.85(1.45–2.38)
P < 0.001Acute care bed
1.68(1.09–2.58)
P = 0.02Observational data: associations, not effects.
Further findings
Moving a patient for ECPR cannulation
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Moving a patient for cannulationNo association with mortality | 0.70 (0.18–2.81) | P = 0.62 | |
| 0.20.5125Adjusted odds ratio (log scale) |
| Outcome | aOR (95% CI) | P value | |
|---|---|---|---|
| In-hospital mortality by agePatients 60-69 vs patients younger than 30 years old | 1.71 (1.17–2.50) | P = 0.006 | |
| In-hospital mortality by agePatients 70 years old or older vs patients younger than 30 years old | 2.27 (1.49–3.48) | P < 0.001 | |
| 0.20.5125Adjusted odds ratio (log scale) |
In-hospital mortality by age
- Advanced patient age associated with increased mortality
Original publication
Survival After Extracorporeal Cardiopulmonary Resuscitation Based on In-Hospital Cardiac Arrest and Cannulation Location: An Analysis of the Extracorporeal Life Support Organization Registry. Crit Care Med. Published 9 October 2024. doi:10.
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