Pediatric anesthesia & critical care

Survival After Intra-Arrest Transport vs On-Scene Cardiopulmonary Resuscitation in Children

JAMA Netw OpenPublished Retrospective cohort study

Main finding · Survival to hospital discharge (propensity-matched cohort)Result — go to the resultRR for survival to hospital discharge 0.81 95% CI 0.59–1.10

Authors' conclusion

In this cohort study of a North American OHCA registry, intra-arrest transport compared with continued on-scene CPR was not associated with survival to hospital discharge among children with OHCA.

Study context

Population
Pediatric patients aged <18 years with emergency medical services (EMS)-treated out-of-hospital cardiac arrest (OHCA), Resuscitation Outcomes Consortium Epidemiologic Registry (10 sites, US and Canada), 2005–20153,680 matched cases
Participants
2,854 patients
Exposure
Intra-arrest transport vs continued on-scene cardiopulmonary resuscitation (CPR)
  • Intra-arrest transportn = 1,892
  • Continued on-scene CPRn = 962reference
Outcome
Survival to hospital discharge
Methodological detailstime-dependent propensity-score matched, multicentre registry
  • Time-dependent propensity-score matched
  • Multicentre registry

Main finding

As reported in the abstract

Survival to hospital discharge (propensity-matched cohort)

RR for survival to hospital discharge

0.81

95% CI 0.59–1.10

Events by group

Intra-arrest transport vs On-scene CPR
RR for survival to hospital discharge 0.81 (95% CI 0.59–1.10)

Observational data: associations, not effects.

Further findings

OutcomeRR for survival to hospital discharge (95% CI)
Survival to hospital discharge (subgroup age <1 year)Intra-arrest transport vs On-scene CPR · lower survival with intra-arrest transport0.52 (0.33–0.83)
Survival to hospital discharge (subgroup age ≥1 year)Intra-arrest transport vs On-scene CPR · no association1.22 (0.77–1.93)

Survival to hospital discharge by timing of intra-arrest transport

Not modified by timing of intra-arrest transport
  • Interaction P = .10

Original publication

Survival After Intra-Arrest Transport vs On-Scene Cardiopulmonary Resuscitation in Children. JAMA Netw Open. Published 1 May 2024. doi:10.1001/jamanetworkopen.2024.11641

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