ICU sedation, delirium & recovery

Survival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

In this cohort study, 4 of 5 middle-aged and older adults died or survived with severe impairment within 2.5 years of LTCH hospitalization. Better preadmission survival prognosis and functional and cognitive status were associated with lower risk of an adverse outcome

Study context

Population
Adults aged ≥50 years in the Health and Retirement Study with an LTCH admission, 2003–2016, and Health and Retirement Study (HRS) interviews before admissionmedian age 75 years
Participants
396 adults
Outcome
Death or severe impairment (dependencies in ≥2 ADLs or dementia)
Follow-up
2.5 years after LTCH hospitalization
Methodological detailslinked Medicare claims, Data analyzed between November 1, 2021, and June 30, 2023
  • Linked Medicare claims
  • Data analyzed between November 1, 2021, and June 30, 2023

Main finding

As reported in the abstract

Death or severe impairment · 2.5 years

Died or survived with severe impairment (functional, cognitive, or both)

318

80%

Lee index score, per 5-point increase: AOR

3.2

95% CI 1.7 to 6.0

Severe vs no baseline impairment: AOR

4.5

95% CI 1.3 to 15.4

Observational data: associations, not effects.

Further findings

Severe impairment at baseline

Severe impairment
125 (28%)

Original publication

Survival, Function, and Cognition After Hospitalization in Long-Term Acute Care Hospitals. JAMA Netw Open. Published 1 May 2024. doi:10.1001/jamanetworkopen.2024.13309

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