Pediatric anesthesia & critical care

Sustained Performance of Cardiac Arrest Prevention in Pediatric Cardiac Intensive Care Units

JAMA Netw OpenPublished Observational cohort study

Main finding · Risk-adjusted IHCA incidenceResult — go to the resultOdds ratio 1.03 95% CI 0.89–1.19

Authors' conclusion

In this cohort study of all CICU admissions across 17 hospitals, IHCA prevention was feasible and sustainable; the established reduction in risk-adjusted IHCA rate was maintained for at least 2 years after the end of the CAP project.

Study context

Population
Admissions to pediatric cardiac intensive care units (CICUs) of 17 PC4 cardiac arrest prevention (CAP)-participating hospitals17 hospitals
Participants
16,284 vs 13,082
Exposure
Follow-up era vs CAP era
  • Follow-up eran = 16,284
  • CAP eran = 13,082reference
Outcome
Risk-adjusted IHCA incidence rate across all admissions
Methodological detailsmulticentre, before-after comparison of eras, hospital survey
  • Multicentre
  • Before-after comparison of eras
  • Hospital survey

Main finding

Risk-adjusted IHCA incidence

Odds ratio

1.03

95% CI 0.89–1.19

By group

Follow-up era vs CAP era
OR 1.03 (95% CI 0.89–1.19)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Risk-adjusted in-hospital cardiac arrest (IHCA) incidence in medical, surgical, high-risk subgroups (subgroup)

No difference between eras

Hospital quality improvement (QI) sustainability score vs odds of IHCA in follow-up vs CAP era

Lower score correlated with higher odds of IHCA (correlation coefficient)
−0.58
  • P = .02

Hospitals with ≥1% increase in risk-adjusted IHCA rate in follow-up era

Hospitals with increase
5
These hospitals had significantly lower QI sustainability scores, less adoption of sustainability elements and less persistent engagement

Original publication

Sustained Performance of Cardiac Arrest Prevention in Pediatric Cardiac Intensive Care Units. JAMA Netw Open. Published 3 September 2024. doi:10.1001/jamanetworkopen.2024.32393

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