Cardiac arrest & resuscitation
Symptoms of anxiety and depression after out-of-hospital cardiac arrest: an exploratory dyadic analysis of survivors and their cohabiting spouses or partners from the BOX trial
Authors' conclusion
Symptoms of anxiety and depression did not differ in survivors and their spouse/partners. Higher age was associated with lower scores of anxiety and depression among survivors, and poorer self-rated health with higher symptom-scores in both.
Study context
- Population
- Cohabiting survivor-partner dyads after OHCA, BOX trial, 3-month follow-up200 dyads of 321 eligible
- Comparison
- OHCA survivors vs cohabiting spouses/partners
- Primary endpoint
- Symptoms of anxiety and depression (HADS-A anxiety, HADS-D depression)
- Follow-up
- three-month follow-up
Methodological detailsdyadic analysis
- Dyadic analysis
Primary result
As reported in the abstract
| Group | Value | HADS-D median (IQR) |
|---|---|---|
| Survivors | median 4 (IQR 1–7) | 1 (IQR 0-4) |
| Spouses/partners | median 5 (IQR 1–8) | 1 (IQR 0-3) |
Value
Survivorsmedian 4 (IQR 1–7)
Spouses/partnersmedian 5 (IQR 1–8)
HADS-D median (IQR)
Survivors1 (IQR 0-4)
Spouses/partners1 (IQR 0-3)
- Survivors vs Spouses/partners: P = 0.107 — paired comparison
- Survivors vs Spouses/partners: P = 0.290 — paired comparison
Further findings
| Outcome | β (95% CI) | P value |
|---|---|---|
| Age and HADS-A, survivors (adjusted regression) | −0.065 (−0.125 to −0.025) | P = 0.012 |
| Age and HADS-D, survivors (adjusted regression) | −0.040 (−0.090 to −0.00) | P = 0.037 |
Self-rated health (sensitivity analyses)
- Poorer self-rated health associated with higher HADS-A and HADS-D in both parts
- Poorer survivor self-rated health associated with higher HADS-D among spouses/partners
Original publication
Symptoms of anxiety and depression after out-of-hospital cardiac arrest: an exploratory dyadic analysis of survivors and their cohabiting spouses or partners from the BOX trial. Resuscitation. Published 25 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →