Cardiac arrest & resuscitation
Temporal trends in organ donation among cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation
Authors' conclusion
The public health benefits of an established ECPR program extend beyond individual ECPR patient survival, forming a new, previously under-recognized source of transplant donors.
Study context
- Population
- Patients with refractory out-of-hospital-cardiac-arrest (OHCA), mostly initial shockable rhythms, treated with extracorporeal-cardiopulmonary-resuscitation (ECPR), 2016–2023
- Participants
- 419 patients
- Outcome
- Organ donation rate among non-survivors; public health benefit of ECPR (survivors with CPC 1-2 plus non-survivors donating ≥1 solid organ, over total ECPR patients)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Survived neurologically intact
- 116 (27.7%)
- Non-survivors whose families consented to organ donation
- 41 (13.5%) of 303
- Donors with organs harvested
- 38
- Organ transplants
- 74 to 73 recipients
- Accepted organs/donor
- 2.4 ± 0.9
- Organ donors correlated with years since ECPR program initiation
- ptrend = 0.009
- Successful transplants correlated with years since ECPR program initiation
- ptrend = 0.01
- Cumulative public health benefit of ECPR (116 survivors and 38 donors)
- 36.8%
Observational data: associations, not effects.
Further findings
Transplanted organs
- Kidneys
- 43 (58.1%)
- Livers
- 27 (36.5%)
- Lungs
- 3 (4%)
- Heart
- 1 (1.4%)
Patients benefiting from ECPR (organ-failure-free survival)
- Total benefited (116 survivors, 73 organ recipients)
- 189
Consenting donors' characteristics
- Median age
- 51 years
- Male
- 75.6%
Original publication
Temporal trends in organ donation among cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 5 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →