The analgesic effect of transversalis fascia plane block after caesarean section under spinal anaesthesia with intrathecal morphine: a randomised controlled trial
Primary result · Cumulative morphine equivalent opioid doseResult — go to the resultMean difference 13.7 mg 95% CI 4.1–23.2Authors' conclusion
We conclude that transversalis fascia plane bupivacaine 0.25% with adrenaline reduces pain and opioid dose after caesarean section compared with saline 0.9%.
Study context
- Population
- Women after singleton caesarean section under spinal anaesthesia with intrathecal morphine
- Participants
- 52 vs 54
- Comparison
- Saline vs Bupivacaine
- Salinen = 52reference
- Bupivacainen = 54
- Primary endpoint
- Cumulative morphine equivalent opioid dose
- Follow-up
- 24 h
Primary result
As reported in the abstract
Mean difference
13.7 mg
95% CI 4.1–23.2
P = 0.006
By group
Saline vs Bupivacaine
mean difference 13.7 mg (95% CI 4.1–23.2); P = 0.006
Further findings
Time to first postoperative opioid dose
P = 0.054
| Outcome | Mean reduction (points) (95% CI) | P value |
|---|---|---|
| Pain at rest (0-10-point scale) · 48 h | 0.9 (0.2–1.6) | P = 0.013 |
| Pain on movement (0-10-point scale) · 48 h | 1.2 (0.4–2.1) | P = 0.004 |
Original publication
The analgesic effect of transversalis fascia plane block after caesarean section under spinal anaesthesia with intrathecal morphine: a randomised controlled trial. Anaesthesia. Published 14 November 2023. doi:10.
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