Perioperative medicine & outcomes

The association between BMI and postoperative pulmonary complications in adults undergoing non‐cardiac, non‐obstetric surgery: a retrospective cohort study

AnaesthesiaPublished Retrospective cohort study

Authors' conclusion

Patients who were overweight or living with class 1 obesity undergoing non-cardiac, non-obstetric surgery had paradoxically lower risks of postoperative pulmonary complications compared with those of a normal weight.

Study context

Population
Adults undergoing non-cardiac, non-obstetric surgery at a university-affiliated tertiary care hospital, 2019–2023
Participants
125,082 adults
Exposure
BMI categories vs normal weight
Outcome
Incidence of PPCs
Methodological detailssingle-centre, university-affiliated tertiary care hospital, multivariable logistic regression, restricted cubic splines
  • Single-centre
  • University-affiliated tertiary care hospital
  • Multivariable logistic regression
  • Restricted cubic splines

Main finding

As reported in the abstract

PPCs
Each group vs normal weightOdds ratio (95% CI)P value
Underweightadjusted for confounders
1.24(1.12–1.39)
P < 0.001
Overweightadjusted for confounders
0.88(0.83–0.94)
P < 0.001
Class 1 obesityadjusted for confounders
0.82(0.70–0.96)
P = 0.01
Obesity class 2/3adjusted for confounders; similar risk
1.23(0.91–1.66)
P = 0.17
Overall incidence of ≥1 PPC
6671 (5.3%)

Observational data: associations, not effects.

Further findings

Shape of BMI–PPC association (restricted cubic splines)

J-shaped association; lowest risk at BMI (kg.m-2)
27.4

Original publication

The association between BMI and postoperative pulmonary complications in adults undergoing non‐cardiac, non‐obstetric surgery: a retrospective cohort study. Anaesthesia. Published 18 February 2025. doi:10.1111/anae.16573

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