Respiratory failure & ventilation
The Association Between Patient-Ventilator Asynchrony and Clinical Outcomes in Mechanically Ventilated Patients: A Systematic Review
Authors' conclusion
PVA and specifically ineffective triggering and double triggering, are associated with a longer duration of mechanical ventilation and longer ICU length of stay.
Study context
- Population
- Mechanically ventilated patients
- Participants
- 2,672 participants · 19 studies
- Comparison
- Patient-ventilator asynchrony (PVA) vs no PVA
- Outcome
- Clinical outcomes: ICU LOS, mechanical ventilation duration, mortality
Pooled result
As reported in the abstract
Duration of mechanical ventilation and ICU LOS
PVA vs No PVAMean difference, d (95% CI)
Duration of mechanical ventilation
3.29(0.13–6.44)
ICU LOS
3.65(1.20–6.11)
Further pooled results
- Reverse triggering appears to have a potential positive association with outcome
Original publication
The Association Between Patient-Ventilator Asynchrony and Clinical Outcomes in Mechanically Ventilated Patients: A Systematic Review. Crit Care Med. Published 12 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →