The Association Between Socioeconomic Position and Mortality in Patients With Sepsis and Septic Shock—A Systematic Review and Meta-Analysis
Authors' conclusion
We found that several indicators of SEP were associated with increased short-term mortality in patients with sepsis and septic shock.
Study context
- Population
- Adults with sepsis and/or septic shock
- Participants
- 3,951,677 adults · 13 observational studies
- Comparison
- Lower vs higher socioeconomic position
- Outcome
- Mortality
Methodological detailsrandom-effects models, GRADE certainty assessment, QUIPS risk-of-bias assessment
- Random-effects models
- GRADE certainty assessment
- QUIPS risk-of-bias assessment
Pooled result
As reported in the abstract
Mortality by SEP indicator
Estimate (95% CI)
Lack of private insurancehigh certainty
aOR 1.34(1.19–1.51)
Lower neighborhood socioeconomic statusmoderate certainty
aOR 1.35(1.29–1.41)
Lower incomemoderate certainty
aOR 1.06(1.01–1.11)
Lower incomemoderate certainty
aHR 1.51(1.01–2.25)
Less educationlow certainty
aOR 1.33(1.14–1.55)
Unemploymentlow certainty
aOR 1.91(1.00–3.63)
Original publication
The Association Between Socioeconomic Position and Mortality in Patients With Sepsis and Septic Shock—A Systematic Review and Meta-Analysis. Crit Care Med. Published 20 March 2026. doi:10. 1097/ ccm. 0000000000007053
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