Cardiac arrest & resuscitation
The association of duration of resuscitation and long-term survival and functional outcomes after out-of-hospital cardiac arrest
Authors' conclusion
Longer CPR-to-ROSC interval was associated with lower survival at hospital discharge and was influenced by pre-arrest co-morbidities. However, these intervals were not associated with long-term survival or functional outcome among hospital survivors, suggesting early risk of longer CPR-to-ROSC intervals does not persist.
Study context
- Population
- EMS-treated adult Out-of-hospital Cardiac Arrest (OHCA), British Columbia Cardiac Arrest Registry, January 2009 - December 20164,604 (45%) achieved ROSC
- Participants
- 10,241 participants
- Exposure
- CPR-to-ROSC interval ≤10 vs 10-20 vs >20 min
- Outcome
- Survival and functional outcomes at hospital discharge and 1- and 3-year survival
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
Post-discharge survival among hospital survivors (Kaplan-Meier) · 1 and 3 years
1-year survival among hospital survivors
92%
95% CI 90–93%
3-year survival among hospital survivors
84%
95% CI 82–86%
Observational data: associations, not effects.
Further findings
CPR-to-ROSC interval among ROSC patients
- Median CPR-to-ROSC interval
- 15.5 (IQR 9.0-22.9) minutes
Pre-arrest co-morbidities and CPR-to-ROSC interval
- DM, CKD and prior MI associated with longer CPR-to-ROSC intervals
Original publication
The association of duration of resuscitation and long-term survival and functional outcomes after out-of-hospital cardiac arrest. Resuscitation. Published 29 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →