Pediatric anesthesia & critical care

The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation

Perioper Med (Lond)Published Randomised controlled trial

Primary result · Mean recovery timeResult — go to the resultMean difference - 3.3 min 95% CI - 5.16 to - 1.44

Authors' conclusion

Prophylactic CPAP application following therapeutic balloon dilatation in pediatric patients who have developed subglottic stenosis due to acquired or congenital causes appears to effectively shorten recovery time and may have a role in decreasing postoperative pulmonary complications

Study context

Population
Children aged 0 to 12 years with subglottic stenosis undergoing elective balloon dilatation under GA81 analysed
Participants
84 children
Comparison
Prophylactic CPAP vs no CPAP after balloon dilatation
  • CPAPn = 40
  • non-CPAPn = 41reference
Primary endpoint
Duration of recovery time
Methodological detailsprospective, double-blinded, parallel-group, single-centre, Retrospectively registered
  • Prospective
  • Double-blinded
  • Parallel-group
  • Single-centre
  • Retrospectively registered

Primary result

Mean recovery time

Mean difference

- 3.3 min

95% CI - 5.16 to - 1.44

P = 0.0007

As reported in the abstract

Secondary outcomes

Lower odds of bronchospasm, tracheal secretion, need for intensive care and tracheostomy, but higher odds of intubation, with CPAP vs controls; not statistically significant

Original publication

The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation. Perioper Med (Lond). Published 23 January 2025. doi:10.1186/s13741-024-00478-5

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