Neuroanesthesia & neurocritical care
The effect of restrictive vs. liberal fluid protocols on ocular parameters in patients undergoing prone spine surgery: a randomized controlled trial
Authors' conclusion
Compared to the restrictive fluid protocol, the liberal fluid protocol increased IOP but not ONSD in patients undergoing prone spine surgery.
Study context
- Population
- Patients undergoing prone spine surgeryall completed
- Participants
- 97 patients
- Comparison
- Liberal vs restrictive fluid protocol
- Primary endpoint
- Intraocular pressure (IOP) and optic nerve sheath diameter (ONSD), both eyes
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
IOP, supine to end of surgery · end of surgery
| Group | Value | Supine baseline | P vs supine |
|---|---|---|---|
| Liberal | 31 (SD 5) mmHg | 12±3mmHg | p<0.001 |
| Restrictive | 28 (SD 4) mmHg | 12±2 | p<0.001 |
Value
Liberal31 (SD 5) mmHg
Restrictive28 (SD 4) mmHg
Supine baseline
Liberal12±3mmHg
Restrictive12±2
P vs supine
Liberalp<0.001
Restrictivep<0.001
- Liberal vs Restrictive: P = 0.019 — statistically significant difference
Further findings
- Optic nerve sheath diameter (ONSD), supine to end of surgery — ONSD increased from 5.3±0.3mm supine to 5.5±0.3mm at end of surgery in both groups · no statistically significant difference
- P < 0.001 · P > 0.05
Original publication
The effect of restrictive vs. liberal fluid protocols on ocular parameters in patients undergoing prone spine surgery: a randomized controlled trial. Perioper Med (Lond). Published 12 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →