Pain medicine

The effect of smoking on postoperative pain and nausea, and vomiting

Perioper Med (Lond)Published Prospective observational cohort study

Authors' conclusion

For this two-centre LMIC cohort study, current smoking status was not an independent predictor of early POP or PONV.

Study context

Population
Adults (≥ 18 years) undergoing elective surgery under GA in two West Bank of Palestine tertiary referral hospitalsmedian age 38 years
Participants
200 adults
Exposure
Current smokers vs nonsmokers
  • Smokersn = 90
  • Nonsmokersn = 110reference
Outcome
Nausea (presence and severity on VAS), vomiting (number of episodes) and pain (presence and severity on VAS)
Follow-up
24 h after surgery
Methodological detailstwo-centre, multivariable logistic regression, Six months, two tertiary referral hospitals, West Bank of Palestine
  • Two-centre
  • Multivariable logistic regression
  • Six months, two tertiary referral hospitals, West Bank of Palestine

Main finding

As reported in the abstract

Postoperative nausea, vomiting and pain
Smoking status not significantly associated with severities of nausea, vomiting or pain
all p > 0.05

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

The effect of smoking on postoperative pain and nausea, and vomiting. Perioper Med (Lond). Published 4 December 2025. doi:10.1186/s13741-025-00634-5

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