The effectiveness of a brief intervention for intensive care unit patients with hazardous alcohol use: a randomized controlled trial
- terminated early
- Terminated early due to slow recruitment during the pandemic
Authors' conclusion
As underpowered, our study cannot reject or confirm the hypothesis that a single BI early after critical illness is effective in reducing the amount of alcohol consumed compared to TAU. However, a considerable number in both groups reduced their alcohol consumption.
Study context
- Population
- Emergency admitted adult ICU patients with hazardous alcohol use (Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) > 5 women, > 6 men), three Finnish university hospitals
- Participants
- 234 participants
- Comparison
- Brief intervention vs treatment as usual
- BIn = 117
- Treatment as usual (TAU)n = 117reference
- Primary endpoint
- Self-reported alcohol consumption during the preceding week
- Follow-up
- 6 and 12 months after randomization
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Alcohol intake during the preceding week
| Group | Value | 12 months median (IQR) |
|---|---|---|
| BI | median 6.5 (IQR 0–141) g | 24 g (0-146) |
| TAU | median 0 (IQR 0–72) g | 0 g (0-96) |
Value
BImedian 6.5 (IQR 0–141) g
TAUmedian 0 (IQR 0–72) g
12 months median (IQR)
BI24 g (0-146)
TAU0 g (0-96)
- BI vs TAU: P = 0.544 — 6 months
- BI vs TAU: P = 0.157 — 12 months
Secondary outcomes
Abstinence · 6 months
Abstinence · 12 months
| Outcome | BIMedian - | TAU | P value |
|---|---|---|---|
| Median change in AUDIT-C from baseline · 6 months | 1 (IQR - 4 to 0) | median 2 (IQR - 6 to 0) | P = 0.144 |
| Median change in AUDIT-C from baseline · 12 months | 3 (IQR - 5 to - 1) | median - 4 (IQR - 7 to - 1) | P = 0.187 |
Mortality
- No between-groups difference in mortality
Original publication
The effectiveness of a brief intervention for intensive care unit patients with hazardous alcohol use: a randomized controlled trial. Crit Care. Published 30 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →