The effects of intrathecal morphine on urinary bladder function and recovery in patients having a cesarean delivery – A randomized clinical trial
Authors' conclusion
This study is the first randomized trial to demonstrate that the addition of ITM to the standardized mixture of prilocaine and sufentanil significantly delayed micturition.
Study context
- Population
- ASA I–II women scheduled for elective cesarean delivery under spinal anesthesia
- Participants
- Fifty-six women
- Comparison
- Spinal prilocaine + sufentanil with vs without intrathecal morphine
- PSMn = 30
- PSn = 24reference
- Primary endpoint
- Time to micturition
Primary result
As reported in the abstract
Time to first micturition
P < 0.001
Secondary outcomes
| Outcome | PSM | P value |
|---|---|---|
| Time to first urge to urinateSignificantly prolonged in PSM | 8 (range 6–10) hours | P < 0.001 |
| Need for bladder re-catheterization (800 mL criterion) | Two events |
- Need for bladder re-catheterization (800 mL criterion): after 6 and 8 h respectively
Original publication
The effects of intrathecal morphine on urinary bladder function and recovery in patients having a cesarean delivery – A randomized clinical trial. Anaesth Crit Care Pain Med. Published 25 June 2023. doi:10.
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