Cardiac arrest & resuscitation
The impact of alternate defibrillation strategies on time in ventricular fibrillation
Authors' conclusion
DSED and VC reduced VF duration and increased the likelihood of ROSC and survival compared to standard shocks.
Study context
- Population
- Patients with refractory VF in out-of-hospital cardiac arrest (OHCA) enrolled in the Double Sequential External Defibrillation for Refractory VF RCTshocks, 342 patients
- Participants
- 834 patients
- Comparison
- Double sequential external defibrillation (DSED) and VC vs standard shocks
- Standardn = 429reference
- VCn = 218
- DSEDn = 187
- Primary endpoint
- VF duration (VF time after each shock)
Primary result
As reported in the abstract
Median VF time
P = 0.003
Further findings
Shocks leading to ROSC — DSED vs Standard
P < 0.001
Shocks leading to survival to hospital discharge — DSED vs Standard
P = 0.002
| Outcome | Standard | VC | DSED | P value |
|---|---|---|---|---|
| Shocks leading to ROSCVC vs Standard | P < 0.002 | |||
| Shocks leading to survival to hospital dischargeVC vs Standard | P = 0.049 | |||
| Shocks with VF not terminatedDSED vs Standard | 40.6% | — not stated in the abstract | 29.9% | P = 0.013 |
— not stated in the abstract
Original publication
The impact of alternate defibrillation strategies on time in ventricular fibrillation. Resuscitation. Published 17 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →