The impact of BMI on arrest characteristics and survival of patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation

Kosmopoulos, M; Kalra, R; Alexy, T; Gaisendrees, C; Jaeger, D; Chahine, J; Voicu, S; Tsangaris, A; Gutierrez, AB; Elliott, A; Bartos, JA; Yannopoulos, D

doi:10.1016/j.resuscitation.2023.109842

Cardiac arrest & resuscitation

The impact of body mass index (BMI) on arrest characteristics and survival of patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation

ResuscitationPublished 15 May 2023Retrospective cohort study

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Authors' conclusion

ECPR yields clinically meaningful long-term survival in patients with BMI > 30 kg/m2. However, the resuscitation time is significantly prolonged, and the overall survival significantly lower compared to patients with BMI ≤ 30 kg/m2.

Study context

Population: Patients with refractory VT/VF OHCA treated with ECPR, December 2015 to October 2021224 required VA ECMO
Participants: 283 patients

Exposure: BMI >30 vs BMI ≤30 kg/m²
BMI > 30n = 133
BMI ≤ 30n = 150reference
Outcome: Survival to hospital discharge

Methodological detailssingle-centre

Single-centre

Main finding

As reported in the abstract

BMI ≤ 3048%

BMI > 3029.3%

P < 0.001

Observational data: associations, not effects.

Further findings

Need for VA ECMO support

P = 0.015

BMI > 3085.7%

BMI ≤ 3073.3%

CPR duration

Significantly prolonged CPR duration with BMI > 30

Four-year mortality · 4 years

Low and not significantly different between the two groups: P = 0.32

Original publication

The impact of BMI on arrest characteristics and survival of patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 15 May 2023. doi:10.1016/j.resuscitation.2023.109842

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