One-year liver graft survival from brain-dead donors treated with ECPR for out-of-hospital cardiac arrest

doi:10.1016/j.resuscitation.2026.111219

Cardiac arrest & resuscitation

One-year liver graft survival from brain-dead donors treated with extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest

ResuscitationPublished 23 Jul 2026Retrospective observational study

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Authors' conclusion

There was no statistically significant difference in one-year liver graft survival between donors treated with ECPR for refractory OHCA and other donors.

Study context

Population: Brain-dead patients who donated at least one organ, single centre, January 2011–June 2024actual liver donors
Participants: 15 vs 27

Exposure: ECPR vs Control
ECPRn = 15
Controln = 27reference
Outcome: Liver graft survival
Follow-up: One year

Methodological detailssingle-centre

Single-centre

Main finding

As reported in the abstract

ECPR80%12 of 15

Control89%24 of 27

P = 0.65

Observational data: associations, not effects.

Further findings

Liver retrieval in potential donors

P < 0.01

ECPR39%

Control79%

Donor age

P < 0.01

ECPR47 yearsrange 36–54

Control70 yearsrange 48–79

Peak lactate

P < 0.01

ECPR9.4 mmol/Lrange 6.9–12.4

Control3.0 mmol/Lrange 2–5.7

Liver retrieval in potential donors: 15/38 vs 27/34 potential donors

Original publication

One-year liver graft survival from brain-dead donors treated with ECPR for out-of-hospital cardiac arrest. Resuscitation. Published 23 July 2026. doi:10.1016/j.resuscitation.2026.111219

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