Cardiac arrest & resuscitation
The impact of COVID-19 pandemic on out-of-hospital cardiac arrest: An individual patient data meta-analysis
Pooled result · OHCA incidence and bystander CPR by regional weekly COVID-19 incidenceResult — go to the resultOdds ratio 0.49 95% CI 0.29–0.81Authors' conclusion
During the first COVID-19 pandemic wave, there was higher OHCA incidence and lower bystander CPR rate in regions with a high-burden of COVID-19. COVID-19 was also associated with a change in patient characteristics and lower survival independently of COVID-19 incidence in the region where OHCA occurred.
Study context
- Population
- Out-of-hospital cardiac arrests (OHCA) patients in 97 regions
- Participants
- 49,882 patients · 10 studies
- Comparison
- First COVID-19 pandemic wave vs pre-COVID reference period
- Outcome
- OHCA incidence and bystander CPR by regional weekly COVID-19 incidence
Pooled result
As reported in the abstract
Odds ratio
0.49
95% CI 0.29–0.81
P = 0.005
First COVID-19 pandemic wave vs pre-COVID reference period
OR 0.49 (95% CI 0.29–0.81); P = 0.005
Further pooled results
Medical etiology
P < 0.001
OHCA at home
P < 0.001
Shockable initial rhythm
P < 0.001
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Pre-hospital death, survival to hospital admission, survival to dischargePre-hospital death · independently associated | 1.73 (1.55–1.93) | P < 0.001 | |
| Pre-hospital death, survival to hospital admission, survival to dischargeSurvival to hospital admission · independently associated | 0.68 (0.64–0.72) | P < 0.001 | |
| Pre-hospital death, survival to hospital admission, survival to dischargeSurvival to discharge · independently associated | 0.50 (0.46–0.54) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
Original publication
The impact of COVID-19 pandemic on out-of-hospital cardiac arrest: An individual patient data meta-analysis. Resuscitation. Published 10 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →