Cardiac arrest & resuscitation
Out-of-Hospital Cardiac Arrest Following the COVID-19 Pandemic
An erratum to this article was published (JAMA Netw Open, 5 Feb 2024 ↗)
Authors' conclusion
In this cohort study, survival with good neurological outcome at hospital discharge following OHCA increased significantly after the COVID-19 pandemic.
Study context
- Population
- Patients with out-of-hospital cardiac arrest (OHCA) in whom emergency medical services (EMS) initiated or continued resuscitation, 10 Spanish regions (>28 million inhabitants)
- Participants
- 14,732 patients
- Exposure
- Postpandemic vs pandemic vs prepandemic periods
- Prepandemicn = 6,372
- Pandemicn = 1,409reference
- Postpandemicn = 6,951
- Outcome
- ROSC, overall survival, and survival with good neurological outcome (unimpaired or minimally impaired cerebral performance)
- Follow-up
- Hospital discharge
Methodological detailsmulticentre, 10 Spanish regions EMS, Data analysis performed in July 2023
- Multicentre
- 10 Spanish regions EMS
- Data analysis performed in July 2023
Further findings
| Outcome | Pandemic | Postpandemic | Estimate | P value | |
|---|---|---|---|---|---|
| Incidence of OHCA with resuscitation attemptPostpandemic vs Pandemic | rate ratio for OHCA with resuscitation attempt 4.93 (95% CI 4.66–5.22) | P < 0.001 | |||
| Incidence of futile resuscitation for OHCAPostpandemic vs Pandemic · lower incidence in postpandemic period | rate ratio for futile resuscitation 0.81 (95% CI 0.71–0.92) | P < 0.001 | |||
| ROSC at hospital admissionPostpandemic vs Pandemic | 20.5% | 30.5% | RR for ROSC 1.08 (95% CI 1.06–1.10) | P < 0.001 | |
| Overall survival at discharge · hospital dischargePostpandemic vs Pandemic | 7.6% | 11.2% | RR for survival 1.45 (95% CI 1.21–1.75) | P < 0.001 | |
| 0.20.5125Ratio (log scale) |
- Incidence of futile resuscitation for OHCA — Futile resuscitation incidence
- 2.1 per 100 000 person-years vs 1.3 per 100 000 person-years
Original publication
Out-of-Hospital Cardiac Arrest Following the COVID-19 Pandemic. JAMA Netw Open. Published 2 January 2024. doi:10. 1001/ jamanetworkopen. 2023. 52377
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