ICU sedation, delirium & recovery

The impact of religion on changes in end-of-life practices in European intensive care units: a comparative analysis over 16 years

Intensive Care MedPublished Comparative analysis of two prospective observational studies

Authors' conclusion

Changes in end-of-life practices observed over 16 years appear unrelated to religious affiliations of ICU patients or their treating physicians, but the effects of religiosity and/or culture could not be assessed.

Study context

Population
Adult ICU patients who died or had limitations of life-sustaining therapy in 22 European intensive care units (ICUs) (Northern, Central, Southern Europe)
Participants
4,592 patients · 22 ICUs
Exposure
Ethicus-2 vs Ethicus-1
  • Ethicus-2n = 1,785
  • Ethicus-1n = 2,807reference
Outcome
Changes in end-of-life practices regarding patient/physician religious affiliations
Follow-up
16 years
Methodological detailsEthicus-1 and Ethicus-2, multicentre, 22 European ICUs, 3 regions
  • Ethicus-1 and Ethicus-2
  • Multicentre
  • 22 European ICUs
  • 3 regions

Main finding

As reported in the abstract

End-of-life practices by religion
  • No significant changes in end-of-life practices for any religion over 16 years
  • Distribution of end-of-life practices by religion and region comparable between the two studies

Observational data: associations, not effects.

Further findings

Withholding

Withdrawing

Physician religious affiliation

Treating physicians (not patients) commonly reported no religious affiliation
18%

End-of-life discussions, mortality, time until first decision

End-of-life discussions with patients/families/physicians increased; mortality and time until first decision decreased

Original publication

The impact of religion on changes in end-of-life practices in European intensive care units: a comparative analysis over 16 years. Intensive Care Med. Published 9 October 2023. doi:10.1007/s00134-023-07228-z

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