Variability in forgoing life-sustaining treatment practices in critically Ill patients with hospital-acquired bloodstream infections: a secondary analysis of the EUROBACT-2 international cohort
Authors' conclusion
Economic and regional disparities significantly impact end-of-life decision-making in ICUs.
Study context
- Population
- Non-COVID-19 ICU patients with hospital-acquired bloodstream infections (HABSI) who died in hospital or within 28 days after HABSI, 265 centers worldwide, June 2019-January 2021519 died
- Participants
- 1,589 patients
- Comparison
- Patient, pathogen, center and country-level factors associated with decisions to forgo life-sustaining treatment
- Primary endpoint
- Death preceded by a decision to forgo life-sustaining treatment
Methodological detailsmulticentre, univariable mixed logistic regression with random center effect
- Multicentre
- Univariable mixed logistic regression with random center effect
Primary result
As reported in the abstract
Decision to forgo life-sustaining treatment among deaths
Deaths following a decision to forgo life-sustaining treatment, 191 of 519
36.8%
Further findings
Geographical differences
- No reported decisions to forgo life-sustaining treatment in African countries and fewer in the Middle East vs Western Europe, Australia, and Asia
Mortality
- Died, 519 of 1589
- 32.7%
Original publication
Variability in forgoing life-sustaining treatment practices in critically Ill patients with hospital-acquired bloodstream infections: a secondary analysis of the EUROBACT-2 international cohort. Crit Care. Published 31 August 2024. doi:10.
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