Cardiac arrest & resuscitation
The International Cardiac Arrest Research Consortium Electroencephalography Database
Authors' conclusion
The I-CARE consortium electroencephalography database provides a comprehensive real-world clinical and electroencephalography dataset for neurophysiology research of comatose patients after cardiac arrest.
Study context
- Population
- Patients ≥16 years comatose after ROSC following cardiac arrest with continuous EEG monitoring; 7 academic or teaching hospitals, US and Europe56,676 hours of continuous EEG
- Participants
- 1,020 patients
- Outcome
- Neurologic outcome (best CPC)
- Follow-up
- 3-6 months
Methodological detailsdatabase development, partly prospective and partly retrospective
- Database development
- Partly prospective and partly retrospective
Main finding
As reported in the abstract
Died
n = 603, 59%
Severe neurologic disability (Cerebral Performance Category (CPC) 3 or 4)
48
5%
Good functional recovery (CPC 1-2)
369
36%
Observational data: associations, not effects.
Further findings
Mean EEG recording duration by neurologic outcome
- Significant variability by outcome; range for CPC 1 and CPC 4, respectively
- 53-102 hr
Epileptiform activity ≥1 Hz for ≥1 hour
- All patients
- 258 patients (25%)
- CPC 1-2
- 19%
- CPC 3-5
- 29%
Burst suppression for ≥1 hour
- CPC 1-2
- 207 (56%)
- CPC 3-5
- 635 (97%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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