ICU sedation, delirium & recovery
The optimal dose of mobilisation therapy in the ICU: a prospective cohort study
Authors' conclusion
A mobilisation duration of more than 40 min positively impacts functional outcomes at ICU discharge.
Study context
- Population
- Critically ill patients surviving an ICU stay > 24 h, two ICUs in Germany
- Participants
- 684 patients
- Exposure
- Daily out-of-bed mobilisation ≥ 40 min vs shorter
- Outcome
- Change of Mobility-Barthel until ICU discharge
- Follow-up
- ICU discharge
Methodological detailssingle-centre, two ICUs
- Single-centre
- Two ICUs
Main finding
As reported in the abstract
Daily mobilisation ≥ 40 min an independent predictor of improved functional status at ICU discharge; Average treatment effect (ATE) in three models for baseline characteristics
all three models p < 0.001
Observational data: associations, not effects.
Further findings
Change of Mobility-Barthel until ICU discharge, adjusted for mobilisation parameters (e.g. level of mobilisation)
- Average treatment effect of mobilisation duration disappeared when mobilisation parameters were included
- ATE 1.0 (95% CI - 0.4 to 2.4), p = 0.16
Original publication
The optimal dose of mobilisation therapy in the ICU: a prospective cohort study. J Intensive Care. Published 20 November 2023. doi:10.
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