The Precision Resuscitation With Crystalloids in Sepsis (PRECISE) Trial: A Trial Protocol
Study context
- Population
- Patients with suspicion of group D sepsis in whom a clinician initiates a normal saline order in the emergency department (ED) or intensive care unit (ICU), 6 Emory Healthcare hospitals
- Planned comparison
- Intervention vs Usual care
- Primary endpoint
- Inpatient mortality
- Follow-up
- 30 days
Methodological detailsparallel-group, multihospital, single-blind, pragmatic, Planned ITT analysis
- Parallel-group
- Multihospital
- Single-blind
- Pragmatic
- Planned ITT analysis
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
The Precision Resuscitation With Crystalloids in Sepsis (PRECISE) Trial: A Trial Protocol. JAMA Netw Open. Published 3 September 2024. doi:10. 1001/ jamanetworkopen. 2024. 34197
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