Safety, quality & education

The predictive value of perfusion indices in the triage and clinical management of carbon monoxide poisoning

J Clin Monit ComputPublished Prospective observational study

An erratum to this article was published (J Clin Monit Comput, Dec 2025 ↗)

Authors' conclusion

Perfusion indices, especially PI, may reflect changes in COHb levels and could provide additional information to support triage and monitoring in CO poisoning.

Study context

Population
Patients aged 18 years and older diagnosed with CO poisoning, January 2019 to May 2023
Exposure
HBOT vs NBOT
Outcome
Whether perfusion indices (PI, PVI) can assist in triage and monitoring of CO poisoning
Methodological detailsconsecutive enrolment
  • Consecutive enrolment

Main finding

As reported in the abstract

AUC of PI-1 in predicting the necessity for HBOT

0.935

Observational data: associations, not effects.

Further findings

Change after treatment (perfusion index (PI), pleth variability index (PVI), lactate, carboxyhemoglobin (COHb)) · after 60-min oxygen therapy

PI increased, and PVI, lactate and COHb decreased significantly in both treatment groups
P < 0.001 for all

Original publication

The predictive value of perfusion indices in the triage and clinical management of carbon monoxide poisoning. J Clin Monit Comput. Published 28 October 2025. doi:10.1007/s10877-025-01372-1

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