Safety, quality & education

The role of non-physician providers of anaesthesia: a systematic review

Br J AnaesthPublished Mixed-methods systematic review

Authors' conclusion

There is limited evidence relating to NPA working models, their impact on patient outcomes and on the wider workforce, and the cost-benefit case.

Study context

Population
Non-physician providers of anaesthesia (NPAs); literature on models of working, cost-benefit, workforce impact, patient safety and outcomesincluded reports of 6644 records
Participants
56 participants
Comparison
Nurse anaesthetists vs physician anaesthetists
Outcome
Patient mortality
Methodological detailsupdate of an existing Cochrane review on patient safety and outcomes
  • Update of an existing Cochrane review on patient safety and outcomes

Pooled result

As reported in the abstract

  • Little to no difference in patient mortality, nurse vs physician anaesthetists
  • All included studies had serious risk of bias

Further pooled results

NPA models of working

Different models of working in high-income countries; scope of practice and supervision requirements vary; nurse anaesthetists can practise independently in some countries

Applicability

No studies evaluated NPAs who are not nurses

Safety

Contradictory findings on frequency of complications

Original publication

The role of non-physician providers of anaesthesia: a systematic review. Br J Anaesth. Published 11 August 2025. doi:10.1016/j.bja.2025.06.042

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