The safety of deep sedation for uterine dilation and evacuation in medically complex patients: a retrospective analysis at an urban center (2018–2024)
Authors' conclusion
Intravenous deep sedation for dilation and evacuation is associated with a low incidence of anesthetic-related complications in medically complex patients, including terminations beyond 24 0/7 weeks.
Study context
- Population
- Medically complex patients undergoing elective dilation and evacuation under IV deep sedation at 12 0/7 to 27 6/7 weeks' gestation
- Participants
- 1,165 procedures
- Outcome
- Incidence of periprocedural anesthetic-related complications necessitating endotracheal intubation
Methodological detailssingle-center, 101 (8.7%) >24 0/7 weeks; 397 (34.1%) BMI >30 kg/m²; 104 (8.9%) substance use disorder
- Single-center
- 101 (8.7%) >24 0/7 weeks; 397 (34.1%) BMI >30 kg/m²; 104 (8.9%) substance use disorder
Main finding
As reported in the abstract
Periprocedural anesthetic-related complications necessitating endotracheal intubation
Incidence
0.09%
95% CI
0.012 to 0.6
Observational data: associations, not effects.
Secondary outcomes
- Cases of hypoxemic episodes requiring intervention, n
- 3
- Incidence
- 0.3%
- 95% CI
- 0.08 to 0.8
Original publication
The safety of deep sedation for uterine dilation and evacuation in medically complex patients: a retrospective analysis at an urban center (2018–2024). Int J Obstet Anesth. Published 13 July 2025. doi:10.
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