Obstetric anaesthesia

Pulmonary aspiration of gastric contents during deep sedation for first and second trimester abortion: a systematic review

Int J Obstet AnesthPublished Systematic review of retrospective cohort studies

Authors' conclusion

Deep sedation without intubation appears to be a safe approach for uterine evacuation procedures with pulmonary aspiration and other anesthesia-related adverse events reported rarely.

Study context

Population
Patients undergoing uterine evacuation procedures (first and second trimester abortion) under deep sedation without intubation
Participants
81,120 patients · 6 cohort studies
Outcome
Pulmonary aspiration
Methodological detailsPRISMA guidelines, Databases searched January 1, 2000 to April 13, 2026
  • PRISMA guidelines
  • Databases searched January 1, 2000 to April 13, 2026

Pooled result

As reported in the abstract

Pulmonary aspiration under deep sedation without intubation

Total cases of pulmonary aspiration reported

2

Aspiration of gastric contents

1

Safety

Conversion to intubation (most common secondary anesthesia-related adverse event)

Individuals converted to intubation
5

Original publication

Pulmonary aspiration of gastric contents during deep sedation for first and second trimester abortion: a systematic review. Int J Obstet Anesth. Published 1 July 2026. doi:10.1016/j.ijoa.2026.105231

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