The use of intrathecal morphine in non-abdominal surgery: a scoping review
Authors' conclusion
This review supports the effectiveness of intrathecal morphine in non-abdominal surgery.
Study context
- Population
- Patients undergoing non-abdominal surgery
- Participants
- 4,685 patients · 75 RCTs
- Comparison
- Intrathecal morphine in non-abdominal surgery
- Primary endpoint
- Effectiveness, appropriate dosage and adverse effects of intrathecal morphine
Methodological detailssystematic search, bias assessments
- Systematic search
- Bias assessments
Primary result
As reported in the abstract
Postoperative pain and opioid consumption
- Intrathecal morphine reduced postoperative pain and opioid consumption after spinal, thoracic and orthopaedic lower extremity surgery
Safety
Itching, PONV, urinary retention
- Increased incidence of itching, PONV and urinary retention, particularly in orthopaedic procedures
Delayed respiratory depression
- Absent with low to moderate doses (<500 μg) in the reviewed studies
Original publication
The use of intrathecal morphine in non-abdominal surgery: a scoping review. BJA Open. Published 20 March 2025. doi:10.
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