Perioperative medicine & outcomes
Thoracic epidural analgesia vs. patient-controlled intravenous analgesia for patients undergoing open or laparoscopic colorectal cancer surgery: An observational study
Authors' conclusion
TEA in open or laparoscopic colorectal surgery is associated with moderately better postoperative pain control but does not affect LOS, postoperative morbidity, mortality nor long-term survival.
Study context
- Population
- Adults (ASA I–IV) undergoing open or laparoscopic colorectal cancer surgery, Dutch tertiary-care university hospital, 2014–2016enrolled
- Participants
- 422 adults
- Exposure
- Thoracic epidural analgesia (TEA) vs patient-controlled intravenous analgesia (PCIA)
- TEAn = 110
- PCIAn = 234reference
- Outcome
- Postoperative pain (NRS)
- Follow-up
- POD 1 to 3 inclusive
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
Each group vs PCIAEstimate (95% CI)P value
TEA
estimated NRS difference at rest −0.79(−1.1 to −0.49)
P < 0.001TEA
estimated NRS difference during movement −1.06(−1.39 to −0.73)
P < 0.001Observational data: associations, not effects.
Secondary outcomes
LOS, 30-day complication rate, overall survival at 5 years
- Did not differ between the groups
Original publication
Thoracic epidural analgesia vs. patient-controlled intravenous analgesia for patients undergoing open or laparoscopic colorectal cancer surgery: An observational study. Eur J Anaesthesiol Intensive Care. Published 4 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →