ICU sedation, delirium & recovery
Time-Limited Trials for Patients With Critical Illness: A Review of the Literature
Authors' conclusion
Time-limited trials are endorsed by physicians, align with the priorities of some older adults, and are part of current practice.
Study context
- Population
- Patients with critical illness in the ICU18 empirical studies · 15 ethical analyses
Main finding
As reported in the abstract
- Time-limited trials are part of current US ICU practice; use varies by unit and physician factors
- Some ICU physicians are familiar with, endorse and have participated in time-limited trials
- Some older adults appear to favor time-limited trials over indefinite life-sustaining therapy or comfort-focused care
- Time-limited trials are often implemented incompletely and challenged by systematic barriers
- Predictive modeling studies: prognostic uncertainty decreases over time in the ICU for some patients
- One prospective study of an intervention supporting time-limited trials vs usual ICU care: promising preliminary results
- Ethical analyses describe time-limited trials as a pragmatic approach within withholding/withdrawing life-sustaining therapies
Original publication
Time-Limited Trials for Patients With Critical Illness: A Review of the Literature. Chest. Published 13 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →