Respiratory failure & ventilation
Trajectories of quality of life, return to work, psychopathology, and disability in survivors of the acute respiratory distress syndrome (ARDS): A three-year prospective cohort study (DACAPO)
Authors' conclusion
Most of recovery in HRQoL and RtW occur during the first 12 months, after which a plateau is reached, indicating a chronification for many patients. Contrary to this, however, psychopathological symptoms remain stable, except for depressive symptoms.
Study context
- Population
- ARDS survivors, assessed at 3, 6, 12, 24 and 36 months after ICU discharge
- Participants
- 877 survivors
- Outcome
- Health related quality of life (HRQoL) (SF-12 PCS, MCS), return to work, panic disorder, depressive symptoms, PTSD trajectories
Main finding
As reported in the abstract
- PCS at 3 months, median (IQR 31-43)
- 36
- PCS at 12 months, median (IQR 34-52)
- 42
- MCS at 3 months, median (IQR 32-54)
- 44
- MCS at 12 months, median (IQR 33-57)
- 47
- Return to work at 3 months
- 23.2%
- Return to work at 12 months
- 54.5%
- Major depressive syndrome at 3 months
- 14.2%
- Major depressive syndrome at 36 months
- 8.9%
- Panic disorder, range over follow-up (varied only slightly)
- 5.3% to 7.4%
- Post-traumatic-stress-disorder (PTSD), range over follow-up (varied only slightly)
- 27.1% to 32.6%
Observational data: associations, not effects.
Original publication
Trajectories of quality of life, return to work, psychopathology, and disability in survivors of the acute respiratory distress syndrome (ARDS): A three-year prospective cohort study (DACAPO). J Crit Care. Published 27 June 2023. doi:10.
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