Pediatric anesthesia & critical care
Transfusion targets and adverse events in pediatric perioperative acute Anemia
Authors' conclusion
In transfused patients, there was no association between postoperative hemoglobin values and clinical outcomes, except the need for subsequent transfusion.
Study context
- Population
- Children undergoing noncardiac surgery who received intraoperative RBC transfusions, 2008–2018
- Participants
- 741 procedures
- Outcome
- Initial postoperative hemoglobin and outcomes
Methodological detailssingle-centre, observational, multivariable regression
- Single-centre
- Observational
- Multivariable regression
Main finding
As reported in the abstract
- Transfusion within first 24 postoperative h, per 1 g/dL decrease in initial postoperative hemoglobin
- 1.62 [1.37-1.93]; P < .001 (OR [95% CI])
- Hospital-free days: no significant relationship
- P = .56
- ICU admission: no significant relationship
- P = .71
- Postoperative mechanical ventilation: no significant relationship
- P = .63
- Infectious complications: no significant relationship
- P = .74
Observational data: associations, not effects.
Further findings
Preoperative anemia
- Patients with known preoperative hemoglobin who had anemia
- 498 (68%)
- Of these, preexisting anemia diagnosis in health record
- 14%
Hemoglobin concentrations
- Pretransfusion hemoglobin, median (IQR), g/dL
- 8.1 (7.4-9.2)
- Initial postoperative hemoglobin, median (IQR), g/dL
- 10.4 (9.3-11.6)
Original publication
Transfusion targets and adverse events in pediatric perioperative acute Anemia. J Clin Anesth. Published 2 February 2024. doi:10.
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