Paediatric anaesthesia & critical care
Effect of Thermal Softening of Endotracheal Tubes on Perioperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy: A Randomized Controlled Trial
Authors' conclusion
Warming ETTs to body temperature before intubation was associated with a meaningful reduction in PRAEs-particularly laryngospasm and postoperative coughing-in children undergoing AT.
Study context
- Population
- Children aged 3–9 years scheduled for elective adenotonsillectomy
- Participants
- 254 children
- Comparison
- Thermally softened ETT pre-warmed to 37°C vs room-temperature ETT
- Primary endpoint
- Any PRAE (coughing, oxygen desaturation, laryngospasm or bronchospasm)
- Follow-up
- From extubation through the second postoperative hour
Methodological detailsprospective
- Prospective
Primary result
As reported in the abstract
P = 0.039
Secondary outcomes
Laryngospasm
P = 0.029
Postoperative coughing
P = 0.043
Independent PRAE predictors (multivariable logistic regression)
| aOR (95% CI) | ||
|---|---|---|
| Room-temperature ETT use | 2.29 (1.16–4.54) | |
| Higher Obstructive Sleep Apnea-18 score | 1.04 (1.01–1.07) | |
| 0.20.5125Adjusted odds ratio (log scale) |
Oxygen desaturation, bronchospasm, intraoperative haemodynamic and ventilatory variables
- No significant differences
Original publication
Effect of Thermal Softening of Endotracheal Tubes on Perioperative Respiratory Adverse Events in Children Undergoing Adenotonsillectomy: A Randomized Controlled Trial. Paediatr Anaesth. Published 11 September 2026. doi:10.
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