Perioperative medicine & outcomes
Trends in Comorbidities and Complications Among Octogenarians and Nonagenarians Undergoing Primary Total Joint Arthroplasty in the United States
Authors' conclusion
Although THA/TKA patients appear to be in good health relative to 65- to 70-year-olds, age remains a significant risk factor for increased morbidity.
Study context
- Population
- Patients undergoing total knee and hip arthroplasty (TKA, THA), Premier Healthcare database, 2006 to 2022
- Exposure
- Patients aged 80 to 88 and 89+ vs 65 to 70 years undergoing TKA/THA
- Outcome
- Major complications (multivariable models)
Methodological detailsPremier Healthcare database, multivariable models
- Premier Healthcare database
- Multivariable models
Main finding
As reported in the abstract
Major complications
Each group vs 65 to 70Odds ratio (95% CI)
80 to 88TKA, 2006
2.2(2.0–2.4)
89+TKA, 2006
2.7(2.0–3.7)
80 to 88TKA, 2022
1.8(1.6–2.1)
89+TKA, 2022
2.0(1.5–2.8)
80 to 88THA, 2006
2.5(2.1–3.0)
89+THA, 2006
3.7(2.7–5.1)
80 to 88THA, 2022
2.1(1.8–2.4)
- 89+ · THA, 2022; CI as printed
- OR 2.7 (95% CI 2.1–2.4)
Observational data: associations, not effects.
Further findings
Anaesthesia type (TKA)
- Neuraxial anesthesia used more frequently among older patients undergoing TKA
LOS
- Mean LOS for both TKA and THA continuously decreased over time
Comorbidity burden
- Octogenarian and nonagenarian TKA recipients had fewer comorbidities than 65- to 70-year-olds; reverse among THA recipients
Original publication
Trends in Comorbidities and Complications Among Octogenarians and Nonagenarians Undergoing Primary Total Joint Arthroplasty in the United States. Anesth Analg. Published 23 July 2025. doi:10.
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