Obstetric anesthesia

Trends in Maternal Mortality From Obstetric Hemorrhage in France: 15 Years of Confidential Enquiry Into Maternal Deaths

Anesth AnalgPublished Retrospective analysis of national confidential enquiry data

Authors' conclusion

Maternal mortality by obstetric hemorrhage decreased dramatically in France between 2001 and 2015, particularly mortality due to uterine atony. Among women who died, we detected fewer instances of substandard transfusion management or critical care.

Study context

Population
Hemorrhage-related maternal deaths in France, 2001–2015, French Confidential Enquiry into Maternal Deaths
Participants
19 vs 54
Exposure
2013 to 2015 vs 2001 to 2003
  • 2013 to 2015n = 19
  • 2001 to 2003n = 54reference
Outcome
MMR from obstetric hemorrhage
Methodological detailsdescriptive trend study, comparison by triennium
  • Descriptive trend study
  • Comparison by triennium

Main finding

As reported in the abstract

MMR from obstetric hemorrhage (per 100,000 livebirths)
GroupValueLivebirths
2001 to 20032.3 of 100,000 livebirths2,391,551
2013 to 20150.8 of 100,000 livebirths2,412,720

Value

2001 to 20032.3 of 100,000 livebirths
2013 to 20150.8 of 100,000 livebirths

Livebirths

2001 to 20032,391,551
2013 to 20152,412,720

Observational data: associations, not effects.

Further findings

Maternal deaths due to uterine atony

Hemodynamic continuous monitoring among women who died

Vasopressor infusion therapy among women who died

Time to transfusion therapy initiation

Outcome2001 to 20032013 to 2015
Extubated during active hemorrhage17%0 events
Preventable maternal deaths due to hemorrhage · 2013 to 2015— not stated in the abstract88%

— not stated in the abstract

  • Hemodynamic continuous monitoring among women who died: denominators 30 and 18
  • Vasopressor infusion therapy among women who died: denominators 30 and 18
  • Extubated during active hemorrhage: denominators 30 and 18

Time to transfusion therapy initiation

Transfusion therapy initiated more frequently and earlier in 2013 to 2015

Preventable maternal deaths due to hemorrhage · 2013 to 2015

Main improvable care factors: delays in diagnosis and surgical management, particularly after cesarean delivery

Original publication

Trends in Maternal Mortality From Obstetric Hemorrhage in France: 15 Years of Confidential Enquiry Into Maternal Deaths. Anesth Analg. Published 23 May 2024. doi:10.1213/ane.0000000000006864

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