Cardiac arrest & resuscitation
Trends in the incidence and outcomes of cardiopulmonary resuscitation-induced consciousness in out-of-hospital cardiac arrest: a retrospective study
Main findingResult — go to the resultOdds ratio 2.71 95% CI 2.38–3.09Authors' conclusion
Over the 16-year study period, the annual incidence of CPRIC increased, and patients with CPRIC found to have better OHCA survival outcomes.
Study context
- Population
- Adults (≥16 years) with Out-of-hospital Cardiac Arrest (OHCA), Victorian Ambulance Cardiac Arrest Registry, 2008–2024
- Participants
- 43,402 OHCA events
- Exposure
- Cardiopulmonary resuscitation induced consciousness (CPRIC) vs no CPRIC
- CPRICn = 1,438
- Outcome
- Incidence and trends of CPRIC; association of CPRIC with survival to hospital discharge
Methodological detailsregistry-linked
- Registry-linked
Main finding
As reported in the abstract
Odds ratio
2.71
95% CI 2.38–3.09
Events by group
CPRIC
3.3%
1438
CPRIC vs No CPRIC
OR 2.71 (95% CI 2.38–3.09)
- Annual incidence of CPRIC increased over time (IRR)
- 1.083 (95% CI 1.07-1.10)
- Incidence increased across all arrest rhythms
- P < 0.001 for all
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Survival to hospital discharge by CPRIC phenotype (subgroup)CPRIC interfering vs No CPRIC | 2.36 (2.04–2.74) | |
| Survival to hospital discharge by CPRIC phenotype (subgroup)CPRIC non-interfering vs No CPRIC | 4.09 (3.17–5.29) | |
| 0.20.5125Odds ratio (log scale) |
Factors associated with CPRIC
- Younger age, calendar year, cardiac aetiology, public location, witnessed arrest, initial shockable rhythm and mechanical CPR independently associated with CPRIC
ROSC and survival to hospital admission
- CPRIC associated with ROSC and survival to hospital admission
Original publication
Trends in the incidence and outcomes of cardiopulmonary resuscitation-induced consciousness in out-of-hospital cardiac arrest: a retrospective study. Resuscitation. Published 4 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →