Ultrasound-guided erector spinae plane block for postoperative analgesia in patients undergoing minimally invasive direct coronary artery bypass surgery: a double-blinded randomized controlled trial
Authors' conclusion
Erector spinae plane block provided early effective postoperative analgesia and reduced opioid consumption, time to extubation, and ICU discharge in patients undergoing MIDCAB.
Study context
- Population
- Patients undergoing minimally invasive direct coronary artery bypass (MIDCAB) surgery
- Participants
- 60 patients
- Comparison
- Single-shot ESP block with ropivacaine vs normal saline
- Erector spinae plane block (ESPB)n = 30
- Controln = 30reference
- Primary endpoint
- Numerical rating scale (NRS) pain scores at rest
- Follow-up
- Within 48 hr postoperatively
Methodological detailsdouble-blinded
- Double-blinded
Primary result
As reported in the abstract
NRS pain at rest
ESPB vs ControlEstimated mean difference (99% CI)P value
6 hr
−2.1(−2.7 to −1.5)
P < 0.00112 hr
−1.9(−2.6 to −1.2)
P < 0.00118 hr
−1.2(−1.8 to −0.6)
P < 0.001Secondary outcomes
| Outcome | Estimated mean difference (99% CI) | P value | |
|---|---|---|---|
| NRS pain on deep inspirationESPB vs Control · 6 hr | −2.9 (−3.6 to −2.1) | P < 0.001 | |
| NRS pain on deep inspirationESPB vs Control · 12 hr | −2.3 (−3.1 to −1.5) | P < 0.001 | |
| NRS pain on deep inspirationESPB vs Control · 18 hr | −1.0 (−1.8 to −0.2) | P = 0.01 | |
| −4−202Difference (linear scale) |
Opioid use, time to extubation, time to intensive care unit (ICU) discharge
- ESPB: lower total intraoperative fentanyl use, lower 24-hr hydromorphone consumption, shorter time to extubation and to ICU discharge
Original publication
Ultrasound-guided erector spinae plane block for postoperative analgesia in patients undergoing minimally invasive direct coronary artery bypass surgery: a double-blinded randomized controlled trial. Can J Anaesth. Published 21 November 2023. doi:10.
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