Ultrasound-guided External Oblique Intercostal Plane Block with Ropivacaine for Analgesia after Open Hepatectomy: A Randomized Controlled Study
Primary resultResult — go to the resultMean difference −2.91Authors' conclusion
Preoperative EOI plane block reduced intraoperative and postoperative opioid consumption and improve pain control after open hepatectomy compared to PCIA alone without block-related complications.
Study context
- Population
- Adults scheduled for elective open hepatectomy, Zhongshan Hospital, Shanghai, China
- Participants
- 70 adults
- Comparison
- External oblique intercostal (EOI) vs Saline
- Primary endpoint
- Opioid consumption in IV morphine equivalents
- Follow-up
- 24 h postoperatively
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Mean difference
−2.91
P = 0.019
Secondary outcomes
| Outcome | Difference (mg) | P value |
|---|---|---|
| Opioid consumption (IV morphine equivalents) · 36 h | −4.66 | P < 0.001 |
| Opioid consumption (IV morphine equivalents) · 48 h | −6.06 | P < 0.001 |
Intraoperative fentanyl, resting VAS pain scores, time to first rescue analgesia
- EOI required less intraoperative fentanyl, lower resting VAS pain scores and longer time to first rescue analgesia
Coughing pain scores, QoR-15, LOS, chronic pain
- No significant between-group differences
Safety
- EOI-related complications
- 0 · events
EOI-related complications
- No complications related to EOI detected
Original publication
Ultrasound-guided External Oblique Intercostal Plane Block with Ropivacaine for Analgesia after Open Hepatectomy: A Randomized Controlled Study. Anesthesiology. Published 11 November 2025. doi:10.
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