Safety, quality & education

Understanding and mitigating medication errors associated with patient harm in adult intensive care units: a scoping review

Intensive Care MedPublished Scoping review

An erratum to this article was published (Intensive Care Med, Jul 2025 ↗)

Authors' conclusion

Most medication errors in ICU are identified and intercepted by systems and staff. A minority lead to preventable patient harm and increased length of stay. Decision support embedded in e-prescribing systems, medication reconciliation and review processes and clinical pharmacist activities reduce medication errors and patient harm.

Study context

Population
Adult intensive care unit (ICU) patients; literature on medication errors and preventable adverse drug eventsrecords included
Participants
48 patients
Outcome
Medication errors and preventable adverse drug events in adult ICU
Methodological details7 electronic databases searched; 2960 records identified
  • 7 electronic databases searched; 2960 records identified

Main finding

As reported in the abstract

Rate of serious or life-threatening harm, of all medication errors

1-5%

Interventions or mitigation practices focused on the medication prescription phase

n = 11, 55%

Original publication

Understanding and mitigating medication errors associated with patient harm in adult intensive care units: a scoping review. Intensive Care Med. Published 20 May 2025. doi:10.1007/s00134-025-07938-6

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