Cardiac arrest & resuscitation
Understanding patients with mechanical circulatory support for cardiogenic shock: The role of preceding cardiac arrest
Authors' conclusion
Although 30-day mortality rates were comparable, determinants of mortality differed between OHCA and non-OHCA patients.
Study context
- Population
- AMICS patients who underwent PCI and received mechanical circulatory support (MCS), Netherlands Heart Registration PCI Registry, 2017–2021
- Participants
- 241 patients · 9 hospitals
- Exposure
- Out-of-hospital cardiac arrest (OHCA) vs non-OHCA
- OHCAn = 119
- Outcome
- 30-day mortality
- Follow-up
- 30 days
Methodological detailsmulticentre registry, nine hospitals
- Multicentre registry
- Nine hospitals
Main finding
As reported in the abstract
P = 0.869
Observational data: associations, not effects.
Further findings
Independent predictors of 30-day mortality, overall cohort
- Age, lactate, intubation and multivessel disease independently associated with 30-day mortality
- Multivariable logistic regression
Predictors of 30-day mortality, OHCA (subgroup)
- Age and lactate lost predictive value; resuscitation >30 min, initial non-shockable rhythm and multivessel disease strongly associated with mortality
Predictors of 30-day mortality, non-OHCA (subgroup)
- Age, lactate and IHCA predictive; multivessel disease not associated with 30-day mortality
Patient profile
- OHCA patients had better pre-existing condition, more acute presentation and less frequent multivessel disease
Original publication
Understanding patients with mechanical circulatory support for cardiogenic shock: The role of preceding cardiac arrest. Resuscitation. Published 25 May 2026. doi:10. 1016/ j. resuscitation. 2026. 111149
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