Unresolved early post‐operative pain trajectory predicts moderate‐to‐severe persistent pain after breast cancer surgery—An observational cohort study
Authors' conclusion
EPOP trajectories can distinguish between resolved and unresolved acute pain after breast cancer surgery, allowing early identification of patients at risk to develop significant PPBCS.
Study context
- Population
- Patients undergoing breast cancer surgery at a French Comprehensive Cancer Centre, December 2017 to November 2018
- Participants
- 608 patients
- Exposure
- Low vs Resolved vs Unresolved
- Lown = 388
- Resolvedn = 182
- Unresolvedn = 38
- Outcome
- Moderate-to-severe persistent pain after breast cancer surgery (NRS ≥4)
- Follow-up
- Until 24 months after surgery
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Persistent pain after breast cancer surgery (PPBCS)
Mild PPBCS
18%
n = 108
Moderate-to-severe PPBCS
9%
n = 52
Observational data: associations, not effects.
Further findings
EPOP trajectory distribution · first 24 h after surgery · K-means clustering
Pain characteristics, moderate-to-severe vs mild PPBCS
- Significantly more neuropathic pain features, pain-related interference and delayed opioid cessation with moderate-to-severe vs mild PPBCS
Original publication
Unresolved early post‐operative pain trajectory predicts moderate‐to‐severe persistent pain after breast cancer surgery—An observational cohort study. Acta Anaesthesiol Scand. Published 6 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →