Validation of a natural language processing algorithm using national reporting data to improve identification of anesthesia-related ADVerse evENTs: The “ADVENTURE” study

Anaesth Crit Care Pain MedPublished Diagnostic accuracy study

Authors' conclusion

This unsupervised ML method provides an accurate, automated, AI-supported search algorithm that ranks and helps to understand complex risk patterns and has greater speed, precision, and clarity when compared to manual human data extraction.

Study context

Population
AE reports by clinicians and healthcare systems to the French National Health accreditor (HAS), January 1, 2009, to December 31, 2020AE reports
Participants
9,559 reports
Comparison
Natural language processing (NLP)/machine learning (ML) model categorisation of AE reports vs expert anesthesiologist validation
Outcome
Categorisation of reported AE
Methodological detailsmachine learning, natural language processing, national reporting data, validation by independent expert anesthesiologists, 135,000 unique de-identified AE reports labelling validated
  • Machine learning
  • Natural language processing
  • National reporting data
  • Validation by independent expert anesthesiologists
  • 135,000 unique de-identified AE reports labelling validated

Performance

As reported in the abstract

Test or modelValueSensitivity, difficult intubationSpecificity, difficult intubationSensitivity, medication errorSpecificity, medication error
Artificial Intelligence (AI) model88%70.9%96.6%43.2%98.9%

Artificial Intelligence (AI) model

Value88%
Sensitivity, difficult intubation70.9%
Specificity, difficult intubation96.6%
Sensitivity, medication error43.2%
Specificity, medication error98.9%

Further findings

Most frequent AE types

Difficult orotracheal intubation
16.9%
Medication error
10.5%
Post-induction hypotension
6.9%

Original publication

Validation of a natural language processing algorithm using national reporting data to improve identification of anesthesia-related ADVerse evENTs: The “ADVENTURE” study. Anaesth Crit Care Pain Med. Published 6 May 2024. doi:10.1016/j.accpm.2024.101390

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