Pediatric anesthesia & critical care
Validation of a Novel Method for Noninvasive Mixed Venous Oxygen Saturation Monitoring in Anesthetized Children
Authors' conclusion
In conclusion, this first clinical application of a novel concept for noninvasive SvO 2 monitoring without the need for a pulmonary artery catheter indicates that Capno-SvO 2 generates absolute values and trending capacity in close agreement with the gold standard reference method.
Study context
- Population
- Children undergoing cardiac catheter interventions, subjected to moderate hemodynamic challenges
- Participants
- 25 procedures
- Exposure
- Capno-SvO2 vs pulmonary artery blood gas CO-oximetry
- Outcome
- Agreement of absolute SvO2 values (Bland-Altman) and trending ability (concordance rate)
Methodological detailsprospective, observational
- Prospective
- Observational
Main finding
As reported in the abstract
Agreement of Capno-SvO 2 with CO-oximetry (Bland-Altman) and trending ability (concordance rate)
Bias
+3 percentage points
Capno-SvO 2
Upper limit of agreement
+11 percentage points
95% CI 9–14
Capno-SvO 2
Lower limit of agreement
−5 percentage points
95% CI −8 to −3
Capno-SvO 2
- Concordance rate (ability to track change)
- 92% (95% CI, 89-96)
Observational data: associations, not effects.
Original publication
Validation of a Novel Method for Noninvasive Mixed Venous Oxygen Saturation Monitoring in Anesthetized Children. Anesth Analg. Published 2 August 2024. doi:10.
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