Cardiac arrest & resuscitation
Validation of the rCAST score and comparison to the Pittsburgh Cardiac Arrest Category (PCAC) and Full Outline of UnResponsiveness (FOUR) scores for prognostication after out-of-hospital cardiac arrest
Authors' conclusion
The rCAST score can reliably predict poor outcome in a United States cohort of OHCA patients regardless of TTM status and outperforms the PCAC score.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) patients admitted January 2014–August 2022, US single centreall scores available
- Participants
- 505 patients
- Exposure
- rCAST vs PCAC vs FOUR scores for prognostication
- Outcome
- Prediction (AUC) of poor neurologic outcome and in-hospital mortality
- Follow-up
- Discharge
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Poor neurologic outcome
| Group | AUC |
|---|---|
| rCAST | 0.815 [0.763-0.867] |
| PCAC | 0.753 [0.697-0.809] |
| FOUR | 0.841 [0.796-0.886] |
AUC
rCAST0.815 [0.763-0.867]
PCAC0.753 [0.697-0.809]
FOUR0.841 [0.796-0.886]
- FOUR vs PCAC: P < 0.001 — FOUR superior
Observational data: associations, not effects.
Further findings
| Outcome | rCAST | PCAC | FOUR | P value |
|---|---|---|---|---|
| In-hospital mortalityrCAST vs PCAC · rCAST superior | P = 0.017 | |||
| AUC | 0.799 [0.751-0.847] | 0.723 [0.673-0.773] | 0.813 [0.770-0.855] | |
| In-hospital mortalityFOUR vs PCAC · FOUR superior | P < 0.001 | |||
| Score valuesMedian | 9.5 (IQR 6.0–11.5) | 4 (IQR 3–4) | 2 (IQR 0–5) |
- In-hospital mortality: AUC 95% CI
Original publication
Validation of the rCAST score and comparison to the PCAC and FOUR scores for prognostication after out-of-hospital cardiac arrest. Resuscitation. Published 11 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →