Venovenous Extracorporeal Membrane Oxygenation Cannulation by Intensivists and Surgeons: A Single-Center Retrospective Noninferiority Analysis of Complications and Outcomes From 2018 to 2023
Main findingResult — go to the resultAdjusted odds ratio 0.84 95% CI 0.47–1.50Authors' conclusion
Venovenous ECMO cannulation by nonsurgeon intensivists was noninferior to that by CTS with respect to complication rates.
Study context
- Population
- Adults with refractory respiratory failure undergoing venovenous extracorporeal membrane oxygenation (ECMO) cannulation and initiation, quaternary academic centre, southeastern US, 2018–2023533 cannulation events
- Participants
- 231 adults
- Exposure
- CCM vs CTS
- Outcome
- Rate of cannulation-related complications
Methodological detailssingle-centre, non-inferiority
- Single-centre
- Non-inferiority
Main finding
As reported in the abstract
Adjusted odds ratio
0.84
95% CI 0.47–1.50
By group
CCM vs CTS
aOR 0.84 (95% CI 0.47–1.50)
Observational data: associations, not effects.
Secondary outcomes
In-hospital mortality
- In-hospital mortality overall
- 29%
- No significant difference or evidence of noninferiority between groups
Cannulation circumstances
- CCM cases had lower rates of vasoactive medication use and mechanical circulatory support and were more often performed in remote settings
Original publication
Venovenous Extracorporeal Membrane Oxygenation Cannulation by Intensivists and Surgeons: A Single-Center Retrospective Noninferiority Analysis of Complications and Outcomes From 2018 to 2023. Crit Care Med. Published 21 August 2025. doi:10.
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